光電納米催化與工業應用研究中心

陳宜鴻
時間:2020-04-19 09:48:09點擊量:

特聘研究員,博士生導師


地址:湖北省武漢市武昌區八一路299號,郵編:430072

郵箱 yihuch@cup.uni-muenchen.de


研究領域:

有機化學,金屬有機


研究方向:

金屬試劑與過渡金屬催化的機理研究;光電納米催化與流動化學的研究。


個人簡介:

  臺灣清華大學化學系本科畢業,2007 年獲得美國Emory大學博士學位(導師: Prof. Frank E. McDonald),以天然物合成為主要課題。然后以洪堡學者身份在慕尼黑大學(Ludwig-Maximilians-Universit?t)從事博士后研究(導師: Prof. Paul Knochel),之后擔任慕尼黑大學研究員。長期從事金屬有機領域的研究。近 5 年的研究方向集中在發展制備空氣中穩定的固態有機鋅試劑,與藥物合成上的應用。201810月起擔任武漢大學高等研究院特聘研究員。


代表性論文:

1. “Cobalt-Catalyzed Electrophilic Amination of Aryl- and Heteroaryl-Zinc Pivalates with NHydroxylamine Benzoates” Chen, Y.-H.; Gra?lS.; Knochel, P. Angew. Chem. Int. Ed. 2018, 57, 1108.

2. “Preparation of Solid Polyfunctional Alkynylzinc Pivalates with Enhanced Air and Moisture Stability for Organic Synthesis” Chen, Y.-H.; Tüllmann, C. P.; Ellwart, M.; Knochel, P. Angew. Chem. Int. Ed. 2017, 56, 9236.

3. “Preparation and Applications of Solid, Salt Stabilized Zinc Amide Enolates with Enhanced Air and Moisture Stability” Chen, Y.-H.; Ellwart, M.; Toupalas, G.; Ebe, Y.; Knochel, P. Angew. Chem. Int. Ed. 2017, 56, 4612.

4. “Solid Organozinc Pivalates: A New Class of Zinc Organometallics with Greatly Enhanced Air- and Moisture Stability” Chen, Y.-H.; Ellwart, M.; Malakhov, V.; Knochel, P. Synthesis 2017, 49, 3215.

5. “Preparation of functionalized organoaluminiums by direct insertion of aluminium to unsaturated   halides.” Bluemke, T.; Chen, Y.-H.; Peng, Z.; Knochel, P.” Nat. Chem. 2010, 2, 313. (Equal contribution with B.T.)

6. “LiCl-mediated preparation of functionalized benzylic indium(III) halides and highly chemoselective palladium-catalyzed cross-coupling in a protic cosolvent” Chen, Y.-H.; Sun, M.; Knochel, P. Angew. Chem. Int. Ed. 2009, 48, 2236.

7. “Total Synthesis of the Sphingolipid Biosynthesis Inhibitor, Fumonisin B1.”  Pereira, C. L.; Chen, Y.-H.; McDonald, F. E. J. Am. Chem. Soc. 2009, 131, 6066.            

8. “Preparation of Aryl and Heteroaryl Indium(III) Reagents by the Direct Insertion of Indium in the Presence of LiCl.” Chen, Y.-H.; Knochel, P. Angew. Chem. Int. Ed. 2008, 47, 7648.            

9. “New Chiral Synthons for Efficient Introduction of Bispropionates via Stereospecific Oxonia-Cope Rearrangement.” Chen, Y.-H.; McDonald, F. E. J. Am. Chem. Soc. 2006, 128, 4568.  





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